One of Qaddafi's sons was killed in a NATO airstrike that targeted Qaddafi's house.

Qaddafi and his wife were in the house at the time.

ADDED: The NYT reports:

“Tonight and only a short time ago, the Western crusader aggression against the Libyan nation continued and proved again that it has no moral foundation, no legal foundation and no political foundation,” said Moussa Ibrahim, the government spokesman. “The attack resulted in the martyrdom of brother Seif al-Arab Muammar el-Qaddafi, 29 years old, and three of the leader’s grandchildren.”...

Footage broadcast on the satellite channel Al Jazeera showed the wreckage of the house, including a wall with an enormous hole and shattered concrete. There was no immediate reaction from NATO or independent confirmation of the attack....

The airstrike against the Qaddafis marked the most significant escalation so far in the Western air campaign intended to help push him from power. In recent days, NATO leaders have described their growing frustration at the resilience of Colonel Qaddafi’s military forces, which have begun to disguise themselves, hide equipment and otherwise evade NATO airstrikes....